My name is Inna Gertsenshteyn (EE-nah  GURTZ-en-shtine), and I'm a 5th year PhD candidate in Medical Physics at the University of Chicago. My co-advisors are Dr. Howard Halpern and Dr. Chin-Tu Chen. We are working on multimodal tumor hypoxia imaging with 18F-Fluoromizonidazole PET, EPR, and DCE-MRI to improve radiation therapy.

Before graduate school I worked as an Image Analyst at Invicro, a global research partner to pharmaceutical, biotech, and contract research organizations, aiming to enhance drug discovery and development. I also participated in a co-op at Biogen in Late Discovery Imaging to gain industry experience in drug development.

My general research interests are in anything to do with multimodal imaging and image analysis. Outside of academia, I enjoy hosting house concerts, coffee dates with friends, going on walks, watching films, and reading books. 

Publications


Small animal IMRT using 3D-printed compensators


Gage Redler, Erik Pearson, Xinmin Liu, Inna Gertsenshteyn, Boris Epel, Charles Pelizzari, Bulent Aydogan, Ralph Weichselbaum, Howard Halpern, Rodney D Wiersma


International Journal of Radiation Oncology, Biology, Physics


The optimal 18F-Fluoromisonidazole PET threshold to define tumor hypoxia in preclinical squamous cell carcinomas using pO2 electron paramagnetic resonance imaging as reference truth.


Inna Gertsenshteyn, Boris Epel, Amandeep Ahluwalia, Heejong Kim, Xiaobing Fan, Eugene Barth, Marta Zamora, Erica Markiewicz, Hsui-Ming Tsai, Subramanian Sundramoorthy, Lara Leoni, John Lukens, Mohammed Bhuiyan, Richard Freifelder, Anna Kucharski, Mihai Giurcanu, Gregory Karczmar Brian Roman, Chien-Min Kao, Howard Halpern, Chin-Tu Chen


EJNMMI


Development of a PET/EPRI combined imaging system for assessing tumor hypoxia


Heejong Kim, Boris Epel, Subraman Sundramoorthy, Hsiu-Min Tsai, Eugene Barth, Inna Gertsenshteyn, Howard Halpern, Yuexuan Hua, Qingguo Xie, Chin-Tu Chen, Chien-Min Kao


Journal of Instrumentation, 2021


Improving tumor hypoxia location in [18]F-Misonidazole PET with Dynamic Contrast Enhanced MRI using quantitative Electron Paramagnetic Resonance partial oxygen pressure images


Inna Gertsenshteyn, Boris Epel, Eugene Barth, Lara Leoni, Erica Markiewicz, Hsiu-Ming Tsai, Xiaobing Fan, Mihai Giurcanu, Marta Zamora, Subramanian Sundramoorthy, Heejong Kim, Richard Freifelder, Mohammed Bhuiyan, Anna Kucharski, Gregory Karczmar, Chien-Min Kao, Howard Halpern, Chin-Tu Chen


Radiology: Imaging Cancer, vol. 3(2), 2021


View all

News and upcoming presentations 

July 18th, 2022: Ph.D. thesis defense scheduled to present my work on “Multi-Modal Imaging of Tumor Hypoxia to Improve Radiation Therapy”.

June 2022: Finished co-op at Biogen in Late Discovery Imaging, and back at the University of Chicago for my last quarter as  a PhD candidate.

March 10th, 2022: Invited talk at O2M Technologies. More info/registration link here.

January 2022: Starting a co-op at Biogen, while still on track to defend my PhD in the summer of 2022.

December 2nd, 2021: Oral presentation at the Radiological Society of North America Annual Meeting on "Validation of multimodal hypoxia imaging using pO2 EPR, FMISO PET, and DCE MRI with H&E, CD31, and HIF1 α staining on SCC7 squamous cell carcinomas." 

July 29th, 2021: Oral presentation at the International Society on Oxygen Transport to Tissue on "Validation and correction of [18]F-Misonidazole PET with pO2 EPR and
DCE-MRI."

June 12th, 2021: Selected as the 1st place CMIIT Young Investigator Award recipient at the Society of Nuclear Medicine and Molecular Imaging 2021 Annual Meeting, for abstract titled “Optimal [18]F-Misonidazole PET threshold to locate SCC7 tumor hypoxia using EPR pO2 as ground truth.”

April 2021: Recipient of an NIH F31 Ruth L. Kirchstein National Research Service Award for my dissertation project: "Correcting [18]F-Misonidazole PET with MRI and EPR to improve hypoxia-guided radiation therapy." 

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